March 2024 Volume 10 Issue 1
MEDICAL SCIENCES JOURNALAntibiotic Stewardship: A Comprehensive Review of Principles, Strategies, Challenges and Clinical Impact
Nashra Afaq, R. Sujatha
- Pages: 1-8
- Abstract >
<p>Antibiotic stewardship refers to coordinated interventions designed to improve and measure the appropriate use of antimicrobial agents by promoting the selection of optimal drug regimens, doses, duration of therapy, and routes of administration. The growing emergence of antimicrobial resistance (AMR) has become a major global public health concern, leading to increased morbidity, mortality, prolonged hospital stay, and healthcare expenditure. Antibiotic stewardship programs (ASPs) aim to optimize antimicrobial therapy while minimizing toxicity, adverse events, and the development of resistance. This review article discusses the principles, objectives, components, implementation strategies, challenges, and outcomes of antibiotic stewardship. Evidence from recent studies demonstrates that effective stewardship programs reduce inappropriate antibiotic use, healthcare costs, multidrug-resistant organism prevalence, and hospital-acquired infections. The review also highlights the importance of multidisciplinary collaboration, microbiological surveillance, infection control practices, education, and policy development in successful stewardship implementation. Strengthening antibiotic stewardship is essential to preserve antibiotic efficacy for future generations</p>
Acceleration and De-escalation of Antibiotic Therapy in Hospitals: A Systematic Review of Antimicrobial Stewardship Strategies, Clinical Outcomes, and Resistance Patterns
R. Sujatha, Nashra Afaq
- Pages: 1-9
Low Prevalence of Pseudomonas aeruginosa Among Septic Burn Patients at a Tertiary Care Hospital: A Prospective Observational Study
Nashra Afaq, R. Sujatha
- Pages: 1-9
Corneal Scraping Revealing Pythium insidiosum Keratitis in a 65-Year-Old Male Farmer: A Case Report
R. Sujatha, Nashra Afaq
- Pages: 1-5
